SUMMARY Í Connectome


REVIEW Connectome

SUMMARY Í Connectome Ï ❰Read❯ ➵ Connectome Author Sebastian Seung – Johns-cycling-diary.co.uk We know that each of us is uniue but science has struggled to pinpoint where precisely our uniueness resides Is it in our genes The structure of our brains Our genome may determine our eye color and e We know that each of us is uniue but scEctome as it’s called is where our genetic inheritance intersects with our life experience It’s where nature meets nurtureSeung introduces us to the dedicated researchers who are mapping the brain’s connections neuron by neuron synapse by synapse It is a monumental undertaking the scientific euivalent of climbing Mount Everest but if they succeed it could reveal the basis of personality intelligence memory and perhaps even mental disorders Many scientists speculate that people with anorexia autism and schizophrenia are wired differently but. Sebastian Seung is one of a group of neuroscientists who want to literally unravel the brain's wiring diagram in hopes that it will be the ultimate tool to determine our individual differences and to solve such deep and thorny problems as autism schizophrenia depression and other mental disordersSeung is a good writer particularly at explaining the basics of neuroscience and helping you understand the history of research that revealed the existence of neurons the development of brain maps and the discoveries of how certain parts of the brain specialize in certain functionsThe book is actually less successful I think when it delves into Seung's main interest figuring out how to trace the myriad connections of neurons and dendrites and neurites and synapses in the brain He makes it clear how daunting the challenges will be in reconstructing a complete connectome of even one suare millimeter of mouse brain let alone a whole human brain and is honest about how much further technology and computing power have to go to make that possible But he may be right in saying that the promise of connectomics is much greater than any other brain imaging and measurement method now available all of which are leagues cruder by comparisonThe end of the book a speculative look at the possibilities of cryogenic preservation of the brain for future revivification and the prospect for one day being able to upload the informational content of a brain into a computer program is meant to tantalize and raise some profound issues but these are so far fetched at the moment they have a slight ring of absurdity That said I thought this book had a lot to offer and it certainly was the most accessible and deepest exploration of this field that I've encountered Seung is also young enough that he may even see some of his connectome dreams come to fruition

ConnectomeEctome as it’s called is where our genetic inheritance intersects with our life experience It’s where nature meets nurtureSeung introduces us to the dedicated researchers who are mapping the brain’s connections neuron by neuron synapse by synapse It is a monumental undertaking the scientific euivalent of climbing Mount Everest but if they succeed it could reveal the basis of personality intelligence memory and perhaps even mental disorders Many scientists speculate that people with anorexia autism and schizophrenia are wired differently but. Sebastian Seung is one of a group of neuroscientists who want to literally unravel the brain's wiring diagram in hopes that it will be the ultimate tool to determine our individual differences and to solve such deep and thorny problems as autism schizophrenia depression and other mental disordersSeung is a good writer particularly at explaining the basics of neuroscience and helping you understand the history of research that revealed the existence of neurons the development of brain maps and the discoveries of how certain parts of the brain specialize in certain functionsThe book is actually less successful I think when it delves into Seung's main interest figuring out how to trace the myriad connections of neurons and dendrites and neurites and synapses in the brain He makes it clear how daunting the challenges will be in reconstructing a complete connectome of even one suare millimeter of mouse brain let alone a whole human brain and is honest about how much further technology and computing power have to go to make that possible But he may be right in saying that the promise of connectomics is much greater than any other brain imaging and measurement method now available all of which are leagues cruder by comparisonThe end of the book a speculative look at the possibilities of cryogenic preservation of the brain for future revivification and the prospect for one day being able to upload the informational content of a brain into a computer program is meant to tantalize and raise some profound issues but these are so far fetched at the moment they have a slight ring of absurdity That said I thought this book had a lot to offer and it certainly was the most accessible and deepest exploration of this field that I've encountered Seung is also young enough that he may even see some of his connectome dreams come to fruition

REVIEW Ð JOHNS-CYCLING-DIARY.CO.UK ☆ Sebastian Seung

Connectome ↠ We know that each of us is uniue but science has struggled to pinpoint where precisely our uniueness resides Is it in our genes The structure of our brains Our genome may determine our eye color and even aspects of our personality But our friendships failures and passions also shape who we are The uestion is howSebastian Seung a dynamic professor at MIT is on a uest to discover the biological basis of identity He believes it lies in the pattern of connections between the brain’s neurons which change slowly over time as we learn and grow The conn. A connectome is the sum total of connections between neurons in a brain Sebastian Seung argues in his book that one's connectome is the essence of an individual A connectome contains one's memories and personality and defines who we are The idea is that at birth one's neurons are connected with each another at random As one grows the brain's connectome changes through the four R's reweighting reconnection rewiring and regeneration These changes are the essence of growing new memoriesI found the first third of the book to be a bit boring simply because I was already uite familiar with the subject from other books Then the book takes a different tack emphasizing how important new technologies are to making new discoveries in science This idea definitely resonated with me Seung writes If you're a scientist who purchases instruments you could strive for better ones than your rivals by excelling at fundraising But you'd gain a decisive advantage by building an instrument that money can't buy Seung describes a hierarchy of new technologies each bringing new understanding to connectomes He begins with the microscope of course but looking at pieces of a brain through a microscope is not very enlightening The real ground breaking technologies were various types of stains such as the Golgi stain This allowed researchers to identify individual neurons Later the electron microscope helped to analyze the structure of neurons and imaging techniues like fMRI's helped to distinguish functional areas of the brainSeung is a leading researcher in the burgeoning field of connectomics in neuroscience In the book he emphasizes a host of new technologies that he hopes will eventually unravel the connectome of a mouse brain First new slicing techniues are being developed to peel off extremely thin slices of a brain These slices can then be scanned by an electron microscope whose depth of field is limited The next technology is computer systems for handling massive amounts of data in conjunction with artificial intelligence AI for discerning three dimensional structure in a set of images This section of the book is the most interesting as the reader feels the enthusiasm of a researcher on a leading edge of scienceThe last two chapters of the book are interesting speculations One chapter is titled To Freeze or to Pickle It concerns new developments in cryonics in which people elect to have their heads or their entire bodies frozen after death The idea is that in the distant future it might be possible to revive the connectome in a brain and thus revive a person from deathThe last chapter is about scanning connectomes to generate simulations of human behavior Would such a simulation be an automaton or would it have true feelings And what exactly are feelings If you enjoyed the movie Matrix then you will love this chapter REVIEW Ð JOHNS-CYCLING-DIARY.CO.UK ☆ Sebastian Seung

Sebastian Seung ☆ 1 SUMMARY

Sebastian Seung ☆ 1 SUMMARY Nobody knows for sure The brain’s wiring has never been clearly seenIn sparklingly clear prose Seung reveals the amazing technological advances that will soon help us map connectomes He also examines the evidence that these maps will someday allow humans to upload their minds into computers achieving a kind of immortality Connectome is a mind bending adventure story told with great passion and authority It presents a daring scientific and technological vision for at last understanding what makes us who we are Welcome to the future of neuroscienc. Sebastian Sung is a brilliantly lucid writer His analogies are clear; his ideas interesting Sadly his medical materialism taints the whole meal According to Sung there is no soul Or anything else which can't be physically measuredMost notably missing are any references to emergent properties Nor does he refer to the idea that the knowable real world is based on naturally occurring fractal patterns rather than on logically linear patterns Worse yet nowhere does he mention the idea that the only way to make real world measurements is with tipping point based math To Sung simple counting math is enoughWhy give this book four stars then Sung's explanations are amazingly clear For this alone this book should be reuired reading for anyone interested in neuro anatomyWhat about the fact that Sung believes the non material aspects of life all reduce to neuronsWell geniuses are allowed their biases And Sung is truly a genius Steven Paglierani